Giant lymph node hyperplasia (Castleman's disease): a clinical study of eight patients.

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Giant lymph node hyperplasia (Castleman's disease): a clinical study of eight patients.

We report on 8 patients with giant lymph node hyperplasia (GLNH), diagnosed over a 10-year period. The age of the patients at diagnosis, the clinical presentation and the histological subtype varied, indicating that GNLH is a heterogeneous condition. One case was associated with liver cirrhosis, and in another patient bacterial endocarditis was diagnosed post mortem. Our study shows that GLNH i...

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Cardiac tamponade secondary to giant lymph node hyperplasia (Castleman's disease)

A unique association of giant lymph node hyperplasia (Castleman's disease) and cardiac tamponade is presented. Although pleural effusions have been previously described with Castleman's disease, the authors believe this to be the first report of pericardial effusion and tamponade with this entity. The development of effusions may be due to an inflammatory syndrome sometimes seen with the plasma...

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Retroperitoneal unicentric Castleman's disease (giant lymph node hyperplasia): case report.

CONTEXT AND OBJECTIVE Castleman's disease, or giant lymph node hyperplasia, is a rare disorder of the lymphoid tissue that causes lymph node enlargement. It is considered benign in its localized form, but aggressive in the multicentric type. The definitive diagnosis is based on postoperative pathological findings. The aim here was to describe a case of retroperitoneal unicentric Castleman's dis...

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Giant lymph node hyperplasia of the mediastinum and refractory anaemia.

An example is described of the syndrome of refractory anaemia in association with the plasma cell variant of giant lymph node hyperplasia of the mediastinum; the anaemia responded to removal of the lymphoid mass. The entity of giant lymph node hyperplasia is discussed and its relationship to the haematological syndrome is considered.

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Angiofollicular lymph node hyperplasia (Castleman).

Six personally observed cases of this lesion are reported and the literature is reviewed. One hundred and thirty-four cases have been reported to date. The lesion has occurred in many sites, but is commonest in the thorax (60%), abdomen (11%), neck (14%), and axilla (4%). Ninety per cent of cases are symptomless or have only the pressure symptoms, 10% have systemic signs, namely, fever, raised ...

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ژورنال

عنوان ژورنال: Postgraduate Medical Journal

سال: 1991

ISSN: 0032-5473

DOI: 10.1136/pgmj.67.786.366